Coronavirus entry: how we arrived at SARS-CoV-2
Aldose reductase (AR) and glutathione reductase (GR) compete for the cofactor NADPH, which results in a decrease in GSH levels, as well as increased OS
In terms of pathogenicity, distinct strains show obvious divergence in core virulence traits: for example, chromosome 7 trisomic strains present attenuated hyphal formation due to NRG1 overexpression, while euploid strains form robust hyphae with stronger tissue adhesion and invasion capabilities (Kakade et al., 2023)
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Biomed Pharmacother 133:110943 Zhang N, Lu C, Chen L (2016) miR-217 regulates tumor growth and apoptosis by targeting the MAPK signaling pathway in colorectal cancer
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